Founded in 1893 in memory of Kezia Payne DePelchin, a remarkable social worker, teacher, and nurse in Houston during the latter half of the 1800s. The orphanage moved to this building upon completion in 1913 and remained here until 1938. Designed by architects Mauran and Russell, the renaissance revival structure features an open arcade on the bottom story and an entryway flanked with Doric pilasters that support a classical cornice. Recorded Texas Historic Landmark - 1984