Landowner Charles E. Graham (1872-1937) in 1908 granted the Wichita Falls and Southern Railroad a route across his property and platted a town at this site. Anarene was named for his wife Annie Lawrence Graham, daughter of pioneer cattleman J. Marion Keen. Graham built a hotel and obtained a post office, cattle pens, dipping vat and other facilities. The town schoolhouse was used for religious services. In 1921 oil was discovered nearby. A refinery was built in 1938. When oil production ceased and the trains stopped running in 1954, Anarene quickly declined. (1976)