The Fort Worth and Rio Grande Railway extended tracks to Comanche in 1890 and built depots and a section house. The St. Louis and San Francisco Railway acquired the line in 1901, and in 1909 built this depot to replace an earlier frame structure. The one-story brick and limestone prairie school style building has a rectangular floor plan, wide overhanging eaves, and a hipped terra cotta tile roof. It operated as the local passenger train station from the time of its construction until 1969. The depot served freight traffic for another dozen years before the rail line was abandoned. The building was then rehabilitated for community use.