This congregation traces its history to the late 1860s, when early settlers of Jonesboro met together in a combination church-school Masonic Lodge building for worship services. W. L. Jones donated in 1871, and the congregation was formally organized that year. Their first building, completed in 1871, was replaced by a succession of structures over the years to meet the needs of the membership. Methodist congregations in the nearby communities of Ames, Pancake, and Turnersville have merged with the Jonesboro Church.