Founded by settlers who came from Griffin, Georgia. In the early 1850s became a flourishing town. Birthplace of John Benjamin Kendrick (1857-1933), Texas cowboy who settled in Wyoming in 1879 after going up the trail for years with herds of cattle. He served in Wyoming State Senate, 1910-1914, Governor, 1914-1916, then as U.S. Senator, 1916-1933. Town of Griffin gradually lost people and businesses to railroad towns after 1872. Last store here was closed 1930.