One of the homes in the early Union Hill settlement, this Greek Revival residence was built about 1860 for Dr. William Henry Gantt (d. 1867), a physician and scientist who later taught at Galveston Medical College. The second owner, 1865-1890, was Henry B. ("Jo-He") Jones, the inventor of a multi-purpose medicinal ointment. The family of Louis Prenzler lived here from 1908 to 1973. The structure was then purchased and restored by Mr. and Mrs. George L. Temple. Recorded Texas Historic Landmark - 1976